Exopolyphosphatase prune1
WebMar 26, 2024 · NMIHBA is caused by biallelic variants in PRUNE1 encoding prune exopolyphosphatase 1. We provide in-depth clinical description of two affected siblings harboring compound heterozygous variant alleles, c.383G>A (p.Arg128Gln), c.520G>T (p.Gly174*) in PRUNE1 . To gain insights into disease biology, we biochemically … WebApr 4, 2024 · The PRUNE1 gene, located on chromosome 1q21.3, encodes a 453 amino acid protein, that is, highly expressed in the human fetal brain and involved in the regulation of neuronal migration and proliferation [ 4 ]. It harbors 2 domains DHH (20–172 amino acids) and DHHA2 (215–359 amino acids).
Exopolyphosphatase prune1
Did you know?
WebThis gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an … Web(Click on the icon in the table below to see search hit context)
WebPRUNE1 is ubiquitously expressed across multiple tissues with widespread central nervous system expression during fetal development in humans ( 5 ). Previous studies have implicated PRUNE1 in a complex network of interactions regulating cell cycle and motility, with elevated PRUNE1 expression associated with cancer metastasis ( 6–8 ). WebOct 26, 2024 · We note that the in vitro exopolyphosphatase activity of Prune is mostly against very short chains (3 to 4 phosphate units in length) (44, 62). In our experiments, Prune was also expressed at...
WebK01514 PRUNE, PPX1; exopolyphosphatase Enzymes [BR: ko01000] 3. Hydrolases 3.6 Acting on acid anhydrides 3.6.1 In phosphorus-containing anhydrides 3.6.1.11 … WebMar 21, 2024 · PRUNE1 prune exopolyphosphatase 1 Gene ID: 58497, updated on 4-Dec-2024 Gene type: protein coding Also known as: PRUNE; DRES17; HTCD37; NMIHBA; …
WebPRUNE1, prune exopolyphosphatase 1 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog PRUNE1, prune exopolyphosphatase 1. Synonyms DRES17, DRES-17, … aram araniWebPrune exopolyphosphatase 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. PRUNE1 (DRES-17, H-PRUNE, HTCD37, PRUNE) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). Read more. Disease related genes. Enzymes. baju adat nikah batakWeb(Click on the icon in the table below to see search hit context) baju adat minangkabau anakWebMar 3, 2024 · exopolyphosphatase PRUNE1: CCP110: centriolar coiled-coil protein of 110 kDa: SEC16A: protein transport protein Sec16A: CRYBG3: very large A-kinase anchor protein: SPAG5: sperm-associated antigen 5: DCP1A: mRNA-decapping enzyme 1A: STON1: stonin-1: DCP1B: mRNA-decapping enzyme 1B: TRAK1: trafficking kinesin … baju adat minangkabau laki-lakiWebThe human protein, encoded by the gene PRUNE1, is 453 amino acid residues long and has a mass of 50,200 daltons. However, there are up to 7 reported isoforms. It is an enzyme of the inorganic diphosphatase class and is a member of … baju adat nagekeoWebMar 21, 2024 · PRUNE1 prune exopolyphosphatase 1 Gene ID: 58497, updated on 4-Dec-2024 Gene type: protein coding Also known as: PRUNE; DRES17; HTCD37; NMIHBA; DRES-17; H-PRUNE See all available tests in GTR for this gene Go to complete Gene record for PRUNE1 Go to Variation Viewer for PRUNE1 variants Summary baju adat minangkabau kartunWebJan 6, 2024 · NMIHBA is caused by biallelic variants in PRUNE1 encoding prune exopolyphosphatase 1. We provide in-depth clinical description of two affected siblings harboring compound heterozygous variant alleles, c.383G > A (p.Arg128Gln), c.520G > T (p.Gly174*) in PRUNE1. To gain insights into disease biology, we biochemically … baju adat nias