Cancer gsea
WebJul 30, 2024 · The GSEA v4.1.0 release includes a number of improvements and bug fixes, including: Improved support for macOS Catalina and above, including updates to file choosers and notarization of the Mac application with Apple. This fixes issues with installation and with access to certain user directories considered restricted by Apple … WebOct 21, 2024 · The potential mechanisms and pathways associated with IGSF10 in breast cancer were explored by performing a gene set enrichment analysis (GSEA). Results: According to TCGA data, qRT-PCR and IHC experiments, levels of the IGSF10 mRNA and protein were significantly decreased in breast cancer tissues. IGSF10 expression was …
Cancer gsea
Did you know?
WebApr 12, 2024 · Pancreatic ductal adenocarcinoma (PDAC), an aggressive and lethal cancer with 5-year overall survival of 10%, is the seventh leading cause of cancer death … WebNearly 85% of lung cancer diagnoses are non–small cell lung cancer (NSCLC) [16]. ... GSEA results elucidate the correlation between TAS treatment for NSCLC and BBC3 expression and unfold protein response, which helps explore the potential therapeutic targets of NSCLC. Additionally, changes in MGLL expression also provide evidence for …
WebJul 7, 2024 · Gene set enrichment analysis (GSEA) was performed using the TCGA dataset. Results: DGKI was overexpressed in gastric tumors and was related to poor prognosis ( p = 0.003). Overexpression of DGKI in GC was significantly correlated with high grade (OR = 1.71 for G3 vs. G2), stage (OR = 2.08 for II vs. Web1 day ago · The GSEA analysis showed that IGFL2 was significantly enriched in signaling and metabolism. IGFL2 may be involved in the development of many types of cancer, influencing the course of cancer with different biological functions. It may also be a biomarker for tumor immunotherapy.
WebIn tumor research, malignant tumor cells can be distinguished from non-malignant cells by GSEA. Zhang et al. (Zhang M et al. Citation 2024a) used scRNA-seq to study the origin of gastric metaplastic cells and gastric cancer heterogeneity via GSEA of malignant and non-malignant cells. Compared to non-malignant epithelial cells, malignant ... WebDec 7, 2024 · Similarly, we performed GSEA for KEGG pathways associated with cancer. In both cases, we found that these pathways were upregulated in younger patients within the AA group and in older patients within the NAA group (FDR < 0.05; Figures S2A and S2B). Interestingly, young LGG patients were associated with increased activation of VEGF, …
WebConsistent with previous studies [56, 57], our GSEA data also suggested that KIF2C is involved in the regulation of DNA replication and cell cycle control, which might be also responsible for its role in cancer development. Dysfunction of KIF2C may result in erroneous kinetochore-microtubule attachments, leading to the formation of lagging ...
WebDec 8, 2009 · Tumourigenesis was analysed using sorted cells and total RNA was subjected to gene expression profiling and gene set enrichment analysis (GSEA). We showed that several breast cancer cell lines ... how do i find my property assessee numberWebAug 18, 2024 · The Cancer Genome Atlas. GSEA: Gene set enrichment analysis. FAP: Fibroblast activation protein-α ... how much is singapore taxWebDec 23, 2015 · However, the first such gene set appears only at rank 114 and thus, despite being statistically significant, would more likely be overlooked in a routine interpretation of the GSEA results. Repeating GSEA with the 50 hallmarks finds 12 that are significantly enriched (FDR < 0.25, Table S2). The three top hallmarks correspond to the biological ... how do i find my product key for windows 11WebMar 23, 2024 · KEGG and GSEA analyses showed that GSN was vital in the functions and proteoglycans processes in cancer, chemokine signaling pathway and other immune-related pathways, DNA methylation and cell cycle. Discussion: In conclusion, GSN possesses the ability to be a predictive, diagnostic, and immune indicator in pan-cancer. how do i find my profile pictureWeb(A) Venn plot of the GSEA results of the GSE65858 and The Cancer Genome Atlas head and neck squamous cell carcinoma datasets. (B) Bubble plot of the significant gene sets. … how do i find my profileWebJul 27, 2024 · The fast GSEA method is a typical FCS method, and outperforms the standard GSEA approach in its running time and prediction accuracy . Utilizing the RNA … how much is single bus fare londonWebSep 3, 2024 · Enrichment analysis was performed through gene ontology and gene set enrichment analysis (GSEA). Results: ANXA4 was identified as hub immune-related gene between AF and sinus rhythm. Expression levels of ANXA4 increased in diverse cancer types. Survival analysis suggested prognostic significance of ANXA4 expression levels in … how do i find my promotion points